In approximately 10% of patients, acute pancreatitis is complicated by
formation of acute fluid collections, necrosis, abscess, or pseudocys
ts.(1) These changes may remain confined to the pancreas or may extend
to the lesser sac, the pararenal spaces, the root of the small bowel
mesentery, or the transverse mesocolon. Occasionally, inflammatory cha
nges and fluid collections involve more distant sites such as the medi
astinum, the pelvis, or subcapsular collections in the spleen or liver
. Radiographic imaging by ultrasonography and contrast-enhanced comput
ed tomography has proven to be valuable for detection of complications
of acute pancreatitis.(2) Imaging has a significant impact on patient
management and facilitates the choice between conservative treatment
vs surgical or percutaneous radiological intervention.(3-7) Large simp
le fluid collections such as chronic pseudocysts are often readily acc
essible to percutaneous drainage. More commonly, however, patients pre
sent with complex, multiloculated fluid collections.(8) Attempts at pe
rcutaneous drainage frequently present a technical challenge and requi
re careful planning of a safe access route. The purpose of this articl
e is to illustrate a variety of potential access routes and to discuss
their advantages and disadvantages based on our experience with percu
taneous drainage procedures in patients with complicated pancreatitis.