NEONATAL WILMS-TUMOR

Neonatal renal tumors are very rare. We have identified 15 cases of Wi lms' tumors diagnosed in the first 30 days of life. The most common pr esentation was an abdominal mass on routine newborn examination, and t hree tumors were noted on an antenatal ultrasound. All of the infants underwent primary excision of the tumor. Five infants were not given p ostoperative chemotherapy after surgical excision. One of these childr en had a relapse and later died of progressive disease. The remaining children are alive at a median follow-up of 31 months. Eight of the tu mors had evidence of nephrogenic rests. More frequent follow-up physic al and imaging examinations are indicated in children not given adjuva nt chemotherapy or whose tumors show nephrogenic rests. Copyright (C) 1995 by W.B. Saunders Company