A FACILE ACCESS TO SUBSTITUTED 2-NITROSOPHENOLS AND 2-NITROPHENOLS VIA REGIOSELECTIVE NITROSATION OF RESORCINOL MONOETHERS

Authors
MALESKI RJ KLUGE M SICKER D
Citation
Rj. Maleski et al., A FACILE ACCESS TO SUBSTITUTED 2-NITROSOPHENOLS AND 2-NITROPHENOLS VIA REGIOSELECTIVE NITROSATION OF RESORCINOL MONOETHERS, Synthetic communications, 25(15), 1995, pp. 2327-2335
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
25
Issue
15
Year of publication
1995
Pages
2327 - 2335
Database
ISI
SICI code
0039-7911(1995)25:15<2327:AFATS2>2.0.ZU;2-8
Abstract
Solid sodium nitrite in anhydrous propionic acid is an effective syste m for regioselective nitrosation of the subject compounds. High yields of pure 2-nitroso products are obtained rapidly and efficiently. Atta ck at the 4-position becomes competitive if water is present in the me dium. The 5-alkoxy (but not the 3,5-dialkoxy)-2-nitrosphenols can be e asily oxidized with nitric acid to yield the corresponding 2-nitro com pounds.