GABAPENTIN TREATMENT OF SEIZURES IN ACUTE INTERMITTENT PORPHYRIA

Citation
Wo. Tatum et Sb. Zachariah, GABAPENTIN TREATMENT OF SEIZURES IN ACUTE INTERMITTENT PORPHYRIA, Neurology, 45(6), 1995, pp. 1216-1217
Citations number
10
Categorie Soggetti
Clinical Neurology
Journal title
ISSN journal
00283878
Volume
45
Issue
6
Year of publication
1995
Pages
1216 - 1217
Database
ISI
SICI code
0028-3878(1995)45:6<1216:GTOSIA>2.0.ZU;2-7
Abstract
Most antiepileptic drugs (AEDs) available have demonstrated porphyroge nicity in hepatic porphyrias. Gabapentin is a new AED not appreciably metabolized by the liver in humans. We report two patients with acute intermittent porphyria successfully treated with gabapentin without it s inducing porphyric crisis.