MOLECULAR COCRYSTALS OF CARBOXYLIC-ACIDS .21. THE ROLE OF SECONDARY GROUP-INTERACTIONS IN ADDUCT FORMATION BETWEEN 2-AMINOPYRIMIDINE AND SUBSTITUTED BENZOIC-ACIDS - THE CRYSTAL-STRUCTURES OF THE ADDUCTS WITH O-PHTHALIC ACID, O-NITROBENZOIC ACID, O-AMINOBENZOIC ACID AND M-AMINOBENZOIC ACID

The crystalline adducts of 2-aminopyrimidine (2-ap) with a series of m ainly ortho-substituted benzoic acids, o-phthalic acid (opht) [(2-ap)( opht)] (1), 2-nitrobenzoic acid (2-nba) [(2-ap)(2-bna)(2)] (2), 2-amin obenzoic acid (2-aba) [(2-aba) [(2-ap)(2-aba)(2)] (3) and 3-aminobenzo ic acid (3-aba) [(2-ap)(3-aba)] (4) have been prepared and their hydro gen-bonding motifs characterized by using single-crystal X-ray diffrac tion. The role of substituent groups in secondary associations with co crystal formation is considered for the 2-aminopyrimidine system.