PANCREATOBLASTOMA IN AN OLDER ADULT

We present a case of pancreatoblastoma in a 61-year-old man. To our kn owledge, this is the oldest patient with this tumor to be reported. Or iginally regarded as a microadenocarcinoma, the tumor was composed of small cells, sometimes in acinar groups with clusters of squamoid cell s. it also showed acinar and neuroendocrine features by immunohistoche mistry. Staining for trypsin and several neuroendocrine markers was wi despread and intense in the smaller, majority-type cells. There was fa int staining for some neuroendocrine markers in the larger squamoid ce lls. By electron microscopy both exocrine secretory and neurosecretory dense core granules were found. Modern methods of immunohistochemistr y and greater understanding of rare tumor types allowed reclassificati on of this tumor.