Da. Bell et al., AN ALCOHOL RECOGNITION MOTIF - CLEAR EVIDENCE OF BINDING-SITE COOPERATIVITY IN THE COMPLEXATION OF CYCLOHEXANEDIOLS BY NEUTRAL POLYAZA-CLEFTS, Tetrahedron letters, 36(24), 1995, pp. 4155-4158
A polyaza-cleft is found to bind a variety of alcohol functional group
s via two hydrogen bonds. The tethering of two clefts yields cooperati
vity between binding sites.