CONCISE SYNTHESIS OF YINGZHAOSU-C AND EPI-YINGZHAOSU-C BY PEROXYL RADICAL CYCLIZATION - ASSIGNMENT OF RELATIVE CONFIGURATION

Authors
BOUKOUVALAS J POULIOT R FRECHETTE Y
Citation
J. Boukouvalas et al., CONCISE SYNTHESIS OF YINGZHAOSU-C AND EPI-YINGZHAOSU-C BY PEROXYL RADICAL CYCLIZATION - ASSIGNMENT OF RELATIVE CONFIGURATION, Tetrahedron letters, 36(24), 1995, pp. 4167-4170
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
24
Year of publication
1995
Pages
4167 - 4170
Database
ISI
SICI code
0040-4039(1995)36:24<4167:CSOYAE>2.0.ZU;2-6
Abstract
The antimalarial peroxide yingzhaosu C and its diastereoisomer (epi-yi ngzhaosu C) have been synthesized by means of tandem peroxyl radical c yclization-oxygen entrapment. The relative configuration of yingzhaosu C is assigned as cis (3) on account of NMR data for both diastereoiso mers, (2) and (3), and their precursors (8) and (9).