A. Kalan et al., SPONTANEOUS INTERNAL JUGULAR-VEIN THROMBOSIS AND RECURRENT LARYNGEAL NERVE PALSY - A RARE SIMULTANEOUS PRESENTATION OF AN OCCULT MALIGNANT NEOPLASM, Journal of Laryngology and Otology, 110(12), 1996, pp. 1166-1168
Internal jugular vein thrombosis is an uncommon potentially life-threa
tening disorder caused by various conditions. Non-spontaneous internal
jugular vein thrombosis is an uncommon condition associated in the pr
e-antibiotic area with deep-neck infections. Currently iatrogenic trau
ma to the internal jugular vein from catheterisation and repeated intr
avenous injections by drug abusers are the leading causes of thrombosi
s. Spontaneous internal jugular vein thrombosis may occur when there a
re no apparent pre-disposing mechanical or inflammatory causes althoug
h a few of these patients may harbour an occult malignant neoplasm. He
nce, careful investigation and follow-up are vital. Thrombosis in Trou
sseau's syndrome is usually confined to the vascular system of the ext
remities and the viscera. However, secondary to the paraneoplastic hyp
ercoagulable state, thrombosis can occur in the large veins of the hea
d and neck region. We understand this to be the first case where spont
aneous internal jugular vein thrombosis and ipsilateral recurrent lary
ngeal nerve paralysis were the only initial manifestations of an occul
t malignancy.