I. Parhar et al., GENES AND BEHAVIOR AS STUDIED THROUGH GONADOTROPIN-RELEASING-HORMONE (GNRH) NEURONS - COMPARATIVE AND FUNCTIONAL-ASPECTS, Cellular and molecular neurobiology, 15(1), 1995, pp. 107-116
1. GnRH neurons migrate from olfactory placode into the developing bas
al forebrain in a manner which appears remarkably constant across all
vertebrates studied, from fish to human beings. 2. Interruption of thi
s migration can result in Kallmann's Syndrome. Absence of libido by in
dividuals suffering from Kallmann's has allowed us to chart a causal r
oute from a specific gene to a human social behavior.