The death of one fetus in a twin pregnancy can affect both the mother
and the cotwin. Thirty women with twin pregnancies in whom the death o
f one fetus was diagnosed during the second half of pregnancy and a ma
tched group of 30 women with uncomplicated twin pregnancies were inves
tigated. The mean gestational age at delivery for the study and contro
l groups was 32.0 +/- 5.0 (mean +/- SD) weeks and 32.8 +/- 3.9, respec
tively. Twelve pregnancies (40%) were monochorionic. In 15 (50%) the d
iagnosis was made during active labor. The cesarean delivery rate was
higher in the study group than in the control group (18 vs. 11, chi(2)
= 5.43, P < .02). The mean neonatal weight was similar in both groups
(1,586 +/- 725 g vs. 1,543 +/- 691 g). The subgroup of neonates (n =
15) whose cotwins were diagnosed as dead during labor had higher birth
weight as compared to the neonates (n = 15) in whom the diagnosis was
made prior to delivery and were managed expectantly (1,829 +/- 859 vs
. 1,346 +/- 474 g, P < .01). The week of delivery was similar in both
subgroups. Neonatal mortality was 30% and 26.6%, while neonatal morbid
ity was 26.6% and 21.7%, respectively (NS). All the eases of neonatal
mortality were in the subgroup of twins in which the diagnosis of in u
tero death was made before 32 weeks' gestation. The death of one fetus
from a twin pregnancy did Mot significantly jeopardize maternal healt
h, and the neonatal outcome in the remaining twins was primarily a fun
ction of gestational age. An expectant approach to these pregnancies s
eems reasonable.