ADJUVANT SURGICAL AND HORMONAL TREATMENT OF LEIOMYOMATOSIS PERITONEALIS DISSEMINATA - A CASE-REPORT

Leiomyomatosis peritonealis disseminata (LPD) is a rare condition that usually presents during pregnancy or in women during the reproductive years and who are taking oval contraceptives. An unusual case of exte nsive LPD occurred in a 39-year-old woman who teas not pregnant ann ha d never taken oral contraceptives. The condition was treated successfu lly with total abdominal hysterectomy, bilateral salpingo-oophorectomy , omentectomy, limited debulking and adjuvant hormonal therapy with me gestrol acetate. Complete, rapid remission of residual tumor occurred in two months, as substantiated by clinical examination and serial son ography and laparoscopy. This is the first rime that adjuvant hormonal therapy has been used successfully in the treatment of LPD. Radical s urgery in patients with LPD is probably not indicated, and the Else of adjuvant hormonal therapy may accelerate regression of residual tumor . Further evaluation of this form of therapy is recommended.