D. Yishai et al., CHORIOCARCINOMA OF THE BLADDER - REPORT OF A CASE OF PRIMARY TUMOR ORLATE METASTASIS OF A MOLAR PREGNANCY, Journal of reproductive medicine, 40(6), 1995, pp. 482-484
Choriocarcinoma of the bladder was diagnosed in a 54-year-old woman pr
esenting with macroscopic hematuria 17 years following evacuation of a
molar pregnancy. The patient was treated by cystoscopic transurethral
tumour resection followed by three courses of triple-agent chemothera
py and total abdominal hysterectomy with bilateral salpingo-oophorecto
my. Six months later a gradual rise in beta-human chorionic gonadotrop
in levels led to the diagnosis of recurrent bladder tumor at the site
of the previous tumor. The patient underwent a conservative partial cy
stectomy, and 12 months postoperatively there was no evidence of disea
se. It is unclear whether the patient developed a primary urinary blad
der choriocarcinoma or late metastatic disease from the previous molar
pregnancy.