Mf. Ghilardi et al., LEARNING A VISUOMOTOR TRANSFORMATION IN A LOCAL-AREA OF WORK SPACE PRODUCES DIRECTIONAL BIASES IN OTHER AREAS, Journal of neurophysiology, 73(6), 1995, pp. 2535-2539
1. The dependence of directional biases in reaching movements on the i
nitial position of the hand was studied in normal human subjects movin
g their unseen hand on a horizontal digitizing tablet to visual target
s displayed on a vertical computer screen. 2. When initial hand positi
ons were to the right of midline, movements were systematically biased
clockwise. Biases were counterclockwise for starting points to the le
ft. Biases were unaffected by the screen location of the starting and
target positions. 3. Vision of the hand in relation to the target befo
re movement, as well as practice with vision of the cursor during the
movement, temporarily eliminated these biases. The spatial organizatio
n of the biases suggests that, without vision of the limb, the nervous
system underestimates the distance of the hand from an axis or plane
that includes its most common operating location. 4. To test the hypot
hesis that such an underestimate might represent an adaptation to a lo
cal area of work space or range effect, subjects were trained to reach
accurately from right or left positions. After training, movements in
itiated from other locations, including ones that were previously erro
r free, showed new biases that again represented underestimates of the
distance of the initial hand position from the new trained location.
5. We conclude that hand path planning is dependent on learned represe
ntations of the location of the hand in the work space.