Objective: To establish the association of raised levels of antiphosph
olipid antibodies and eclampsia. Methods: Thirty-four patients with ec
lampsia and 34 normotensive controls matched for maternal age, gestati
onal age, and parity were included in the study. All had anticardiolip
in antibodies and lupus anticoagulant performed by established techniq
ues. Results: Seven patients (21%) in the eclamptic group and 8 (24%)
in the control group had raised anticardiolipin antibodies. Conclusion
: No association was found between raised antiphospholipid antibodies
and eclampsia. Of interest is the association between antiphospholipid
antibodies and the HELLP syndrome, which needs further investigation.