Ordinary differential equations are generalized to fractal supports wi
th regular or multifractal properties. This can be done by considering
the corresponding integral equations with respect to the measure. Clo
sed form solutions of simple differential equations (giving rise to ex
ponential, sine and cosine functions) on fractals are presented and th
e generalization to arbitrary differential equations discussed. Some a
pplications of this formalism are presented in connection with multifr
actality.