Mechanical properties of cortical and cancellous bone from eight human
subjects were determined using art ultrasonic transmission technique
Raw computerized tomography (CT) values obtained from scans of the bon
es in water were corrected to Hounsfield units. The correlations betwe
en CT numbers and mechanical property estimated from cortical bone wer
e found to be low (r(2)<0.2), while these relationships for cancellous
bone were found to be higher (r(2)>0.6). These results suggest that C
T values may be useful in predicting mechanical properties only for ca
ncellous bone. Poor correlations were found between modulus in the rad
ial or circumferential direction. and modulus in the superior-inferior
direction for cortical bone whereas good correlations were found betw
een modulus in the anterior-posterior direction or medial-lateral dire
ction, and modulus in the S-I direction for cancellous bone. These res
ults indicate that modulus in. the radial or circumferential direction
could not be predicted from modulus in the S-I direction for cortical
bone, but could be predicted for cancellous bone. The predictive capa
bilities of linear and power models evaluated for cancellous bone alon
e were approximately equal. However, the power function gives a better
fit of data at the low and high density values. The specific relation
ships, depending on the types of bone, that Predict elastic modulus fr
om density and CT numbers were suggested for human, cortical and cance
llous bone. These specific correlations may help a number of researche
rs develop more accurate models; however, these hypotheses should be p
roven by further study.