HAURTXO STUDY - CALCEMIA AND CALCIURIA - REFERENCE VALUES IN OUR PEDIATRIC NORMAL PRODUCTION - CALCIUM IN CHILDHOOD

We have established reference values related to age for calcemia and c alciuria, in 359 healthy children aged 3 to 14 years. As in most publi shed studies we have demonstrated no change in calcemia (mg/dl) and ca lciuria (mg/kg/24 hours) with age or sex, therefore the most useful wa y of expression of calciuria is mg/kg/24 hours. The lower and upper re ference intervals were set at the 3rd and 97th centils. The percentil calciuria values (mg/kg/24 hours and Ca/Cr ratio in spot urine) were h igher than others published. These two methods, mg/kg/24 hours and spo t urine Ca/Cr ratio, show a high correlation (regression analysis) but poor agreement (Altmant test), therefore the spot urine ratio Ca/Cr c an not replace mg/kg/24 hours method to measure calciuria. Nevertheles s ratio values below 0.15 normocalciumria. Otherwise values above 0.15 do not always indicate hypercalciuria.