THE BASIC REPRODUCTION RATIO OF HIV AMONG INTRAVENOUS-DRUG-USERS

Citation
E. Massad et al., THE BASIC REPRODUCTION RATIO OF HIV AMONG INTRAVENOUS-DRUG-USERS, Mathematical biosciences, 123(2), 1994, pp. 227-247
Citations number
28
Categorie Soggetti
Mathematical Methods, Biology & Medicine","Mathematics, Miscellaneous","Biology Miscellaneous
Journal title
ISSN journal
00255564
Volume
123
Issue
2
Year of publication
1994
Pages
227 - 247
Database
ISI
SICI code
0025-5564(1994)123:2<227:TBRROH>2.0.ZU;2-#
Abstract
A new approach for the estimation of the Basic Reproduction Ratio Ro f or HIV among intravenous drug users (IVDU) is proposed. This approach is based in an adaptation of the models proposed by Ross and Macdonald for vector-borne infections. A straightforward adaptation of Macdonal d's model is presented first: biological vectors are replaced by needl es and syringes and we consider a homogeneous population of IVDUs; nex t we present a modified model where several heterogeneities are consid ered. Some of those heterogeneities are due to intrinsic differences b etween needles and syringes and biological vectors; others, such as th ose related to movements of individuals between communities, should ap ply to both biological vectors and injection apparatuses. An example o f the calculations of R(0) for a real IVDUs community is presented.