J. Larsson et al., LOCAL SIGNS AND SYMPTOMS IN RELATION TO FINAL AMPUTATION LEVEL IN DIABETIC-PATIENTS - A PROSPECTIVE-STUDY OF 187 PATIENTS WITH FOOT ULCERS, Acta orthopaedica Scandinavica, 65(4), 1994, pp. 387-393
Local signs and symptoms were evaluated in 187 consecutively presentin
g diabetic patients undergoing amputation for foot ulcers. From admiss
ion until final outcome the patients were treated by the same multidis
ciplinary team both as in- and outpatients. At the time of amputation,
the types of lesions were superficial/deep ulcer (n 17), ulcer with d
eep infection, but without gangrene (n 40), and gangrene with or witho
ut infection (n 130). Healing after a minor amputation (below the ankl
e) occurred in 74 patients, while 88 patients healed after a major amp
utation (above the ankle), and 25 patients died before healing had occ
urred. Deep infection and presence of popliteal or pedal pulses were a
ssociated with healing after minor amputation and so were ulcers on th
e small toes, metatarsal head area and midfoot. Pain, progressive gang
rene, intermittent claudication, and decubital and multiple ulcers wer
e related to healing after major amputation. In a logistic regression
analysis, pain, progressive gangrene and intermittent claudication rem
ained. However, none of these factors excluded healing of a minor ampu
tation and thus selection of amputation level in diabetic patients wit
h foot ulcers cannot be based upon these factors exclusively.