Rg. Shidrawi et al., SYSTEMIC STRONGYLOIDIASIS IN A HUMAN T-LYMPHOTROPIC VIRUS TYPE-1-POSITIVE MAN PRESENTING AS CHRONIC-PANCREATITIS WITH A PANCREATICOBILIARY STRICTURE, European journal of gastroenterology & hepatology, 6(11), 1994, pp. 1059-1062
Objective: To report an unusual case of systemic strongyloidiasis and
to highlight the close association of this condition with human T-lymp
hotropic virus type 1 (HTLV-1) infection in patients from endemic area
s. Patient: A 62-year-old West Indian man, resident in the United King
dom since 1965 and consuming 200 units of alcohol per week, presented
with symptoms of chronic pancreatitis and evidence of malabsorption. h
e had a tight pancreatico-biliary stricture on endoscopic retrograde c
holangio-pancreatography. Pancreatic duct brushings and duodenal and r
ectal biopsies confirmed invasive stronglyoidiasis. Interventions: Pan
creatic duct stenting provided immediate relief of post-prandial pain.
Combination anti-helminthic therapy with thiabendazole and albendazol
e rapidly improved the malabsorption. Outcome: The patient remains wel
l and symptom-free 2 years later, despite continued alcohol abuse. Con
clusions: Systemic strongyloidiasis should be included in the differen
tial diagnosis of patients originating from endemic areas who present
with malabsorption. Their HTLV-1 status should also be established bec
ause of the close association between the two conditions.