GROWTH SUPPRESSION OF MKN-28 HUMAN STOMAC H-CANCER CELLS BY WASABI (EUTREMA-WASABI MAXIM)

Authors
FUKE Y OHISHI Y IWASHITA K ONO H SHINOHARA K
Citation
Y. Fuke et al., GROWTH SUPPRESSION OF MKN-28 HUMAN STOMAC H-CANCER CELLS BY WASABI (EUTREMA-WASABI MAXIM), J JPN SOC F, 41(10), 1994, pp. 709-711
Citations number
NO
Categorie Soggetti
Food Science & Tenology
Journal title
JOURNAL OF THE JAPANESE SOCIETY FOR FOOD SCIENCE AND TECHNOLOGY-NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI
ISSN journal
1341027X → ACNP
Volume
41
Issue
10
Year of publication
1994
Pages
709 - 711
Database
ISI
SICI code
1341-027X(1994)41:10<709:GSOMHS>2.0.ZU;2-X
Abstract
The water extract fraction of wasabi (Eutrema wasabi Maxim.) markedly suppressed the growth of MKN-28 human stomach cancer cells. When MKN-2 8 cells were cultured with more than 40 mul/ml of the water extract of wasabi, they were underwent morphological alteration with frequent ce ll death. The substances that suppressed the growth of MKN-28 cells we re existed in the fraction consisting of components with molecular wei ghts under 5000. The growth-inhibiting effect on MKN-28 cells was unaf fected by treatment at 90-degrees-C for 10 min. Shinigrin and isothioc yanates which are main components of wasabi had no growth-inhibiting e ffect.