MEASUREMENT OF ORGAN VOLUME BY SINGLE-PHOTON EMISSION COMPUTED-TOMOGRAPHY

The aim of this study was to develop a new algorithm for volume determ ination by single photon emission computed tomography (SPECT). Differe nt algorithms were evaluated through phantom studies. The results show that the algorithm combining moment-preserving bilevel thresholding a nd best-fit Laplacian second derivative edge detection can provide the most accurate measurement of volume. Besides, this method can be util ized in different SPECT systems with no need for further phantom studi es. In patient studies, the results of liver volume calculation have i ndicated that this is a useful technique in clinical medicine.