R. Khooshabeh et al., A CASE-REPORT OF MYCOBACTERIUM-CHELONAE KERATITIS AND A REVIEW OF MYCOBACTERIAL INFECTIONS OF THE EYE AND ORBIT, Tubercle and lung disease, 75(5), 1994, pp. 377-382
Mycobacteria are unusual causes of keratitis and other ocular infectio
ns but the outcome of infection is often serious. We report a case of
keratitis due to Mycobacterium chelonae, a rapidly growing environment
al mycobacterium, in a soft contact-lens wearer, and discuss the diffi
culty and delay in identifying the organism, twice erroneously identif
ied as Nocardia asteroides on morphological grounds. Despite in vitro
susceptibility, the response to anti-bacterial agents was negligible a
nd a second keratoplasty was required after a recurrence of disease at
the donor-host junction. We review the role of mycobacteria as the ca
use of keratitis and other forms of ocular disease.