A 31-year-old man on haemodialysis who developed recurrent attacks of
acute pancreatitis during the treatment of pulmonary tuberculosis is p
resented. The pancreatitis rapidly subsided once isoniazid was withdra
wn, but the problem recurred again upon reintroduction of the drug. Th
ere was no further recurrence during successful treatment with full do
ses of rifampicin and pyrazinamide for 1 year.