It has been proposed that high energy shockwaves could be used to crea
te microfractures in cortical bone. This quality might be exploited cl
inically to perform closed osteotomies and promote healing in nonunion
(15). However, no study has previously documented the effect of shock
waves on cortical bone ''in vivo''. We report an investigation designe
d to demonstrate the effect of shockwaves on mature cortical and heali
ng bone. An osteotomy was performed on the tibiae of 37 lambs; two wee
ks later the operation site was exposed to shockwaves. Three weeks lat
er the lambs were killed and specimens of the bone examined histologic
ally and radiographically. Shockwaves had no effect on the periosteal
surface of mature cortical bone, but on the endosteal surface some new
trabecular bone was seen. Healing of bone was delayed by the shockwav
e therapy. We conclude that there is currently little place for shockw
ave treatment in clinical orthopaedics.