Twenty-seven hunting dogs with local swellings on the thoracic and, or
, abdominal wall, were treated mainly by radical surgery supported by
chemotherapy. The lesions were characterised histopathologically as py
ogranulomatous inflammation. One of the dogs died during surgery becau
se of a technical accident. Four of the dogs underwent further surgery
because of relapse. Treatment was successful in 26 cases, with a mean
observation period of 3.3 years (range, 0.6 to 6.5 years) without sig
ns of disease. In 12 of the 26 dogs which underwent surgery, parts of
grasses (Poaceae family), usually the floret, were found in the lesion
s. Predominantly anaerobic bacteria (including actinomyces) common to
the oropharyngeal tract were isolated from lesions. It is proposed tha
t the plant material is inhaled during open-mouth breathing and, after
migration through the lungs to the peripheral attachment of the diaph
ragm, causes productive inflammation by synergism with endogenous micr
oorganisms of mucous membrane origin.