SUPPRESSION OF SQUAMOUS-CELL CARCINOMA IN HAIRLESS MICE BY DIETARY NUTRIENT VARIATION

Authors
ROBINSON AB HUNSBERGER A WESTALL FC
Citation
Ab. Robinson et al., SUPPRESSION OF SQUAMOUS-CELL CARCINOMA IN HAIRLESS MICE BY DIETARY NUTRIENT VARIATION, Mechanism of ageing and development, 76(2-3), 1994, pp. 201-214
Citations number
12
Categorie Soggetti
Geiatric & Gerontology
Journal title
Mechanism of ageing and development → ACNP
ISSN journal
00476374
Volume
76
Issue
2-3
Year of publication
1994
Pages
201 - 214
Database
ISI
SICI code
0047-6374(1994)76:2-3<201:SOSCIH>2.0.ZU;2-D
Abstract
In experiments involving the induction of squamous cell carcinoma in 1 846 hairless mice that were maintained on a wide variety of diets, it was found that those diets with the least optimum balance of nutrients had the greatest inhibitory effect on growth of cancer. Rate of onset and severity of tumors was caused to vary over a 20-fold range by mea ns of dietary balance alone. These experiments suggest that dietary va riation in general and intentional malnutrition in particular should b e given special attention in the control of existing cancer in humans.