M. Sole et al., THE EFFECT OF PH ON PRODIGIOSIN PRODUCTION BY NONPROLIFERATING CELLS OF SERRATIA-MARCESCENS, Letters in applied microbiology, 19(5), 1994, pp. 341-344
The synthesis of prodigiosin by non-proliferating cells of Serratia ma
rcescens was examined at various pH values between 5.5 and 9.5. During
incubation in unbuffered medium, pH changed and prodigiosin productio
n was similar regardless of the initial pH. Variations in pigment prod
uction were noted when buffers were employed in cultures of non-prolif
erating cells. The optimum pH for prodigiosin production was 8.0-8.5.
Proline oxidase was also measured. The results suggest that the effect
of pH may be related to the amount of proline which can be incorporat
ed into prodigiosin.