N. Khan et al., AMBULATORY BLOOD-PRESSURE AND HEART-RATE IN ADOLESCENTS WITH INSULIN-DEPENDENT DIABETES-MELLITUS, American journal of hypertension, 7(10), 1994, pp. 937-940
There is little information regarding ambulatory blood pressure in ado
lescents with insulin-dependent diabetes. Twenty-four-hour ambulatory
blood pressure and heart rate was studied in 28 normotensive adolescen
ts with insulin-dependent diabetes mellitus (IDDM) and normoalbuminuri
a, and adolescent controls. Ambulatory heart rate was higher during da
y and night (P = .001) in the ZDDM patients, with normal mean diurnal
variation of heart rate and blood pressure. Duration of diabetes relat
ed to diastolic ambulatory blood pressure (r = 0.69, P = .0001) and di
astolic blood pressure burden (r = 0.61, P = .0001) independent of age
, gender, height, body mass index, metabolic control, and albumin excr
etion rate. The ambulatory blood pressure monitor was well accepted in
patients and controls. Ambulatory blood pressure monitoring in adoles
cents detects early changes in relation to duration of insulin-depende
nt diabetes.