The information on therapeutics is moving at a high path for various c
auses. Now, tools for informing correctly the prescriber do exist. How
ever, they require the operation of suitable structures. The mainstem
of the system consists of an intermediairy which should comply with ap
propriate rules. It will work from an exhaustive collection of pertine
nt information. This will allowed by the extensive use of literature d
ata banks and clinical trial registries kept with the help of internat
ional collaboration. If will rank the strength of evidence of the coll
ected data according to their internal validity. If will elaborate ove
rviews from validated data obtained from meta-analysis, and messages r
eadily readable by the users, and accessible whenever needed. Overview
s will be used to set up guidelines, references, editorials... Data ba
nks will be accessible to researchers, teachers, officers concerned by
health care.