FACTORS OF RECURRENCE IN CROHNS-DISEASE

The surgical treatment of complications of Crohn's disease is often po stponed, because of the threat of short gut and high recurrence rates. We reviewed retrospectively 286 cases of intestinal resection to eval uate factors influencing the recurrence of Crohn's disease after surge ry. Recurrence was defined as the need for reoperation. Risk factors u sed as independant variables are all subject of controversy in recent literature. These factors included: smoking, blood transfusion, contam ination, localisation of the disease, length of resection, microscopic margins and the duration of follow-up. A logistic regression model wa s calculated, using recurrence as the dependant variable. The mean fol low-up is 55 months. Kaplan Meier was used to measure the recurrence r ate. Duration of follow-up is the most important variable. The length of resection and the positive margins can statistically predict recurr ence (p = 0,046 et p = 0,016), both having a predictive value of 72 %. A resection with clear margins decreases the recurrence rate signific antly (15%) (p = 0,0025).