This study is based on the observations of 86 pleurodesis done by talc
insufflation during thoracoscopy in 82 patients suffering from benign
(8%) and malignant (92%) pleural effusions. Serial chest films were o
btained on every patient. Chest computed tomography was obtained in te
n patient. The most frequent finding seen in the early phase and one m
onth later was the appearance of loculations (94%) in selective areas
of the thorax. Occasionally they take the appearance of airfluid level
s (22%). These loculations are characteristically located in the axill
ary (60%), intrafissural (30%) and paramediastinal (34%) areas of the
chest. In the late phase with a mean evolution time of 6 months, these
loculations evolve in 77% of patients in areas of pleural thickening.
CT of the chest demonstrates the presence of characteristic pleural t
hickening in the form of coarse (5/12) and/or fine linear densities (7
/12) corresponding to talc deposits, on the pleural surface. These mod
ifications are shown by light microscopy examination of the pleural do
ne at the autopsy.