SYNTHESIS OF A 1-ACETYL-3-ALPHA,6-DIMETHYL-HEXAHYDROAZULENE - VERSATILE INTERMEDIATE FOR THE PREPARATION OF TERPENOIDS WITH BICYCLE[5.3.0]DECANE SYSTEM

Authors
MARCOS IS OLIVA IM MORO RF DIEZ D URONES JG
Citation
Is. Marcos et al., SYNTHESIS OF A 1-ACETYL-3-ALPHA,6-DIMETHYL-HEXAHYDROAZULENE - VERSATILE INTERMEDIATE FOR THE PREPARATION OF TERPENOIDS WITH BICYCLE[5.3.0]DECANE SYSTEM, Tetrahedron, 50(44), 1994, pp. 12655-12672
Citations number
28
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
50
Issue
44
Year of publication
1994
Pages
12655 - 12672
Database
ISI
SICI code
0040-4020(1994)50:44<12655:SOA1-V>2.0.ZU;2-4
Abstract
A new method for the transformation of cycloheptenone 2 into enone 35 through the dione 5 has been achieved in 7 steps with an overall yield of 53%. The cycloheptenone 2 was synthesised from (+/-)-nerolidol. Th e enone 35 is a versatile precursor for the preparation of terpenoids either sesquiterpenes or diterpenes with a bicycle[5.3.0]decane system .