RB KINASES AND RB-BINDING PROTEINS - NEW POINTS-OF-VIEW

Authors
TAYA Y
Citation
Y. Taya, RB KINASES AND RB-BINDING PROTEINS - NEW POINTS-OF-VIEW, Trends in biochemical sciences, 22(1), 1997, pp. 14-17
Citations number
50
Categorie Soggetti
Biology
Journal title
Trends in biochemical sciences → ACNP
ISSN journal
09680004
Volume
22
Issue
1
Year of publication
1997
Pages
14 - 17
Database
ISI
SICI code
0968-0004(1997)22:1<14:RKARP->2.0.ZU;2-B
Abstract
The retinoblastoma protein (RE) binds to a variety of cellular protein s and suppresses cellular growth. Such interactions are regulated by p hosphorylation during the cell cycle by several cyclin-dependent kinas es, known as RE kinases. Clues to the specific physiological roles of different RE kinases have been obtained. Moreover, interesting functio ns of the RE protein, other than control of E2F activity have been fou nd.