Premenstrual syndrome is characterized by an array of somatic, cogniti
ve, affective and behavioral disturbances that recur in cyclic fashion
during the luteal phase of the menstrual cycle. The goal of managemen
t is to control symptoms well enough that the patient can function app
ropriately at all stages of the menstrual cycle. Both the patient and
the physician must acknowledge that premenstrual syndrome is a complex
reproductive disorder with a large number of possible manifestations;
therefore, they must be willing to consider more than one strategy, a
nd they must allow sufficient time to seek out successful therapeutic
options. The patient must play an active role in all stages of managem
ent. Although no specific cure for premenstrual syndrome currently exi
sts, most patients experience significant reduction of symptoms and im
provement of quality of life when a rational individualized approach i
s used. Management may involve pharmacologic, nutritional and psychoso
cial interventions.