NUCLEAR TRANSCRIPTION FACTORS - POTENTIAL TARGETS FOR NEW MODES OF INTERVENTION IN SKIN-DISEASE

Authors
MCKAY IA WINYARD P LEIGH IM BUSTIN SA
Citation
Ia. Mckay et al., NUCLEAR TRANSCRIPTION FACTORS - POTENTIAL TARGETS FOR NEW MODES OF INTERVENTION IN SKIN-DISEASE, British journal of dermatology, 131(5), 1994, pp. 591-597
Citations number
35
Categorie Soggetti
Dermatology & Venereal Diseases
Journal title
British journal of dermatology → ACNP
ISSN journal
00070963
Volume
131
Issue
5
Year of publication
1994
Pages
591 - 597
Database
ISI
SICI code
0007-0963(1994)131:5<591:NTF-PT>2.0.ZU;2-P
Abstract
Many drugs already in use for the treatment of skin disease, including steroids, retinoids, vitamin D derivatives and cyclosporin (CyA), exe rt effects on gene transcription. In this review we briefly outline ho w these drugs work, before proceeding to a consideration of how new dr ugs acting on the transcription process might be used to influence ski n disease.