S. Bilgrami et al., AN UNUSUAL LATE RELAPSE IN PATHOLOGICAL STAGE-I NONSEMINOMATOUS GERM-CELL TUMOR - CASE-REPORT AND REVIEW OF THE LITERATURE, Urologia internationalis, 53(3), 1994, pp. 176-178
Late relapses are exceedingly uncommon in patients with pathologic sta
ge (PS) I non-seminomatous germ cell tumors (NSGCT) of the testis trea
ted with inguinal orchiectomy and retroperitoneal lymph node dissectio
n (RPLND). We describe an unusual patient with PSI NSGCT who relapsed
40 months after surgery. The only evidence of recurrent disease was an
elevated serum alpha-fetoprotein level, and complete remission was ac
hieved following the prompt institution of combination chemotherapy. T
o our knowledge, this is the first report of a late relapse in PSI NSG
CT of the testis manifested only as an elevated tumor marker.