KINETICS OF NITRIC-OXIDE SCAVENGING BY RUTHENIUM(III) POLYAMINOCARBOXYLATES - NOVEL THERAPEUTIC AGENTS FOR SEPTIC SHOCK

Authors
DAVIES NA WILSON MT SLADE E FRICKER SP MURRER BA POWELL NA HENDERSON GR
Citation
Na. Davies et al., KINETICS OF NITRIC-OXIDE SCAVENGING BY RUTHENIUM(III) POLYAMINOCARBOXYLATES - NOVEL THERAPEUTIC AGENTS FOR SEPTIC SHOCK, Chemical communications, (1), 1997, pp. 47-48
Citations number
11
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
1
Year of publication
1997
Pages
47 - 48
Database
ISI
SICI code
1359-7345(1997):1<47:KONSBR>2.0.ZU;2-9
Abstract
The reaction of two representative ruthenium(III) polyaminocarboxylate s with nitric oxide are rapid (k > 10(7) M(-1) S-1 at pH 7.4 and 7.3 d egrees C) forming tight (K = 10(8) M(-1)) ruthenium(II) mononitrosyls.