ACUTE ARTERIAL THROMBOSIS IN A PATIENT WITH BREAST-CANCER AFTER CHEMOTHERAPY WITH 5-FLUOROURACIL, DOXORUBICIN, LEUCOVORIN, CYCLOPHOSPHAMIDE, AND INTERLEUKIN-3

Background. Interleukin-3 (IL-3) is an experimental agent used to amel iorate neutropenia in patients receiving chemotherapy. Arterial thromb otic episodes after use of IL-3 have not been reported previously. Met hods. The case of a patient with Stage III adenocarcinoma of the breas t who developed hypotension and acute cerebellar artery and superior m esenteric artery thrombosis after receiving chemotherapy and treatment with IL-3 is reported. Results. To the authors' knowledge, this is th e first patient with arterial thrombosis reported after treatment with IL-3. Conclusions. Interleukin-5 may be associated with increased pro pensity for thrombosis.