THE DNA-BINDING PROTEIN PUL57 OF HUMAN CYTOMEGALOVIRUS IS A MAJOR TARGET ANTIGEN FOR THE IMMUNOGLOBULIN-M ANTIBODY-RESPONSE DURING ACUTE INFECTION

Authors
VORNHAGEN R HINDERER W SONNEBORN HH BEIN G MATTER L THE TH JAHN G PLACHTER B
Citation
R. Vornhagen et al., THE DNA-BINDING PROTEIN PUL57 OF HUMAN CYTOMEGALOVIRUS IS A MAJOR TARGET ANTIGEN FOR THE IMMUNOGLOBULIN-M ANTIBODY-RESPONSE DURING ACUTE INFECTION, Journal of clinical microbiology, 33(7), 1995, pp. 1927-1930
Citations number
17
Categorie Soggetti
Microbiology
Journal title
Journal of clinical microbiology → ACNP
ISSN journal
00951137
Volume
33
Issue
7
Year of publication
1995
Pages
1927 - 1930
Database
ISI
SICI code
0095-1137(1995)33:7<1927:TDPPOH>2.0.ZU;2-S
Abstract
A small polypeptide from pUL57 of human cytomegalovirus was identified as a major target for the immunoglobulin M antibody response. This an tigen seems to be superior to antigenic fragments from pp150 and p52 i n the identification of sera from acutely infected patients. It may th erefore represent an essential antigen for recombinant immunoglobulin M antibody tests for human cytomegalovirus.