Common bile duct stones are usually associated with stones in the gall
bladder. During the period 1989-1991, however, we encountered 17 patie
nts with common bile duct (CBD) stones without gallbladder stones who
had presented with obstructive jaundice and cholangitis. Their ages ra
nged between 30 and 72 years; 10 were female and seven male. Five of t
hem had a deceptive presentation and were initially misdiagnosed as ha
ving a malignant lesion. It was endoscopic retrograde cholangiopancrea
tography that correctly diagnosed the presence of CBD stones in all 17
patients. Therapeutic sphincterotomy led to subsidence of cholangitis
in 16 patients and retrieval of stones in 13 of them. Three patients
required nasobiliary decompression because stones could not be retriev
ed. One patient required emergency surgery due to flare-up of cholangi
tis. Cholesterol concentration of the retrieved stones was 70-92% of t
he dry weight. Thus, these 17 patients formed a distinct subgroup who
had cholesterol CBD stones with stoneless gallbladder, and five of the
se 17 patients had presentations mimicking malignant lesions.