Aim-To set up a programme of internal laboratory audit in a medical mi
crobiology laboratory. Methods-A model of laboratory based process aud
it is described. Laboratory activities were examined in turn by specim
en type. Standards were set using laboratory standard operating proced
ures; practice was observed using a purpose designed questionnaire and
the data were analysed by computer; performance was assessed at labor
atory audit meetings; and the audit circle was closed by re-auditing t
opics after an interval. Results-Improvements in performance scores (o
bjective measures) and in staff morale (subjective impression) were ob
served. Conclusions-This model of process audit could be applied, with
amendments to take local practice into account, in any microbiology l
aboratory.