In patients with chronic myelogenous leukemia (CML), the Philadelphia
chromosome may be associated with a number of other cytogenetic lesion
s, However, t(11;14)(1q13;q32), found mainly in B-cell lymphoprolifera
tive disorders, has not been previously reported in Ph-positive CML. W
e describe a patient with hematologically typical chronic phase CML in
whom both cytogenetic lesions were found at diagnosis.