RENAL-CELL CARCINOMA WITH TRANSLOCATION (X-1) - FURTHER EVIDENCE FOR A CYTOGENETICALLY DEFINED SUBTYPE

Authors
TONK V WILSON KS TIMMONS CF SCHNEIDER NR TOMLINSON GE
Citation
V. Tonk et al., RENAL-CELL CARCINOMA WITH TRANSLOCATION (X-1) - FURTHER EVIDENCE FOR A CYTOGENETICALLY DEFINED SUBTYPE, Cancer genetics and cytogenetics, 81(1), 1995, pp. 72-75
Citations number
16
Categorie Soggetti
Oncology,"Genetics & Heredity
Journal title
Cancer genetics and cytogenetics → ACNP
ISSN journal
01654608
Volume
81
Issue
1
Year of publication
1995
Pages
72 - 75
Database
ISI
SICI code
0165-4608(1995)81:1<72:RCWT(->2.0.ZU;2-U
Abstract
A renal cell carcinoma from a 15-year-old male had a 49,Y,t(X;1)(p11.2 ;q21), +der(X)t(X;1) (p11.2;q21), +5, -16, +17, +18 karyotype. This is the third report of a translocation involving a breakpoint at Xp11.2 in a renal cell carcinoma in a child. A total of nine cases of renal c ell carcinoma involving Xp11, including this case, have been reported. Of the eight cases for which there ore genetics reports, all are male . patients with renal cell carcinoma with abnormalities at Xp11 appear to be younger than renal cell carcinoma patients overall.