EVIDENCE FOR 5-HYDROXYTRYPTAMINE(1A) RECEPTOR INVOLVEMENT IN THE CONTROL OF PROLACTIN SECRETION IN MAN

Citation
E. Palazidou et al., EVIDENCE FOR 5-HYDROXYTRYPTAMINE(1A) RECEPTOR INVOLVEMENT IN THE CONTROL OF PROLACTIN SECRETION IN MAN, Psychopharmacology, 119(3), 1995, pp. 311-314
Citations number
39
Categorie Soggetti
Neurosciences,Psychiatry,"Pharmacology & Pharmacy",Neurosciences,Psychiatry,"Pharmacology & Pharmacy
Journal title
Volume
119
Issue
3
Year of publication
1995
Pages
311 - 314
Database
ISI
SICI code
Abstract
The effects of pindolol pretreatment (2 days) on prolactin and cortiso l responses to a single dose of (+)-fenfluramine (30 mg po) were exami ned in nine healthy male volunteers. Pindolol pretreatment attenuated the (+)-fenfluramine-induced increase in prolactin concentrations but failed to affect the (+)-fenfluramine-induced cortisol increase. These data provide evidence in support of 5-HT1A receptor involvement in th e regulation of prolactin secretion but question its importance in the regulation of cortisol secretion in man.