Benzodiazepines are known to induce amnesic effects. To specify these
effects more precisely, 40 healthy volunteers were given 15 mg diazepa
m or placebo. Effects on a chain of encoding operations were investiga
ted: activation of memory representations, spreading of activation, se
mantic encoding and organizational processes. The diazepam group perfo
rmed tasks consistently slower, although spreading of activation and s
emantic encoding were not affected by diazepam. Rather, diazepam subje
cts benefited less from opportunities to organize to-be-learned materi
al. It is suggested that cognitive processes are slowed down after dia
zepam intake. This may also have implications for the organization of
to-be-learned material.