From feverfew, Tanacetum parthenium, collected in South America, the g
uaianolide 3,4-epoxy-8-deoxycumambrin B and the eudesmanolide epoxysan
tamarine were isolated. The structures were derived by means of spectr
oscopic methods. The relative stereochemistry of 3,4-epoxy-8-deoxycuma
mbrin B was established by chemical conversion and NOESY experiments.
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