LEONTICINS-D-H, 5 TRITERPENE SAPONINS FROM LEONTICE-KIANGNANENSIS

Five new triterpene saponins, leonticins D-H, were isolated from the t ubers of Leontice kiangnanensis. Based on a combination of chemical de gradation and spectroscopic analysis (negative ion FAB mass spectromet ry and 2D NMR experiments), their structures were characterized as 3-O -alpha-L-arabinopyranosyl-caulophyllogen 28 ta-D-glucopyranosyl-(1-->6 -beta-D-glucopyranoside, anosyl-(1-->2)]-alpha-L-arabinopyranosyl-olea nolic acid ha-L-rhamnopyranosyl(1-->4)-beta-D-glucopyranosyl- beta-D-g lucopyranoside,3-O-[beta-D-glucopyranosyl- (1-->3)]-[beta-D-glucopyran osyl-(1-->2)]-alpha-L- arabinopyranosyl-hederagenin 28-O-alpha-L-rhamn opyranosyl- a-D-xylopyranosyl-(1-->3)-beta-D-galactopyranosyl- (1-->4) -beta-D-glucopyranosyl-(1-->3)-alpha-L- arabinopyranosyl-oleanolic aci d ta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranoside and a-D-xylopyran osyl-(1-->3)-beta-D-galactopyranosyl- (1-->4)-beta-D- osyl-(1-->3)-alp ha-L-arabinopyranosyl-echinocystic acid a-L-rhamnopyranosyl-(1-->4)-be ta-D-glucopyranosyl- (1-->6)-beta-D-glucopyranoside, respectively. Cop yright (C) 1997 Elsevier Science Ltd