Life-threatening bacterial infection is difficult to recognize as well
as treat and continues to be a significant cause of mortality in vete
rinary patients. Death, even in appropriately treated animals, is the
result of the overwhelming systemic release of inflammatory mediators
by the host's body. If early treatment is not instituted, death rapidl
y becomes inevitable. Bacterial infection should be suspected when fev
er, tachycardia, hyperventilation, lethargy, depression, anorexia, vom
iting, diarrhea, and/or pain associated with the probable site of infe
ction are present. Treatment consists of appropriate antibiotic therap
y, aggressive cardiovascular support, and surgical removal of infected
matter.